A SHORT REVIEW OF BIOLOGICAL AND NON-BIOLOGICAL APPLICATIONS OF PYRAZOLE BASED-SCHIFF BASES

Abstract

Schiff bases of pyrazole derivatives have received great attention for the last decades due to their versatility and intriguing properties such as thermal stability, catalytic properties, Anti-tumors, anti-cancers, anti-fungal, antibacterial, anti-microbial anti-proliferative, anti-diabetic, anti-inflammatory, biocidal activities, and also act as a ligand in the field of coordination chemistry. The Schiff base is also known as imine or azomethine. The complexes of Schiff bases containing pyrazole also showed significant inhibitory activity against pathogenic bacterial species

Besides versatile biological applications, the Schiff base of pyrazole and its derivatives are also employed as fluorescent turn-on \ turn-off sensors, optical sensors, corrosion inhibitory, fluorescent camphor, and chemo-sensors. Naked eye sensors are much more interesting nowadays due to their visual detection properties rather than employing complex instrumentation. Recently compounds containing Hydroxynaphtaldehyde and aminothiazole derivatives have been of great interest due to their several biological and non-biological applications such as antifungal, antibacterial, Anticancer, anti-tuberculosis, anti-inflammatory, anti-allergic, antihypertensive, Anti-HIV fungicides and herbicides. Fluorescent chemo-sensor, bio-sorbent, pharmacophore, chromophores, Dyes, and pigment. We offered literature highlighting the significance of selected pyrazole derivatives in many domains and their biological and non-biological applications.