Assessment of C-Reactive Proteins and Albumin in PatientsVisiting Burn and Plastic Surgery Center Peshawar

Abstract

The purpose ofthis study is to assess the clinical significance ofCRP and albumin levels in burn patients, as well as their relationship to outcomes like infection, wound healing, and mortality. - RP levels were considerably higher in the acute period post-burn and positively linked with burn surface size and infection (p < 0.05).A high C-RP toalbumin ratio has been discovered as a potential predictive factor for poor clinical outcomes.C-reactive protein and albumin are useful markers for assessing burn patients earlyonand monitoring themover time.Elevated C-RP showsthe inflammation burden. While hypoalbuminemia may suggest a dietary deficiency and forecast complications. Monitoring these indicators can help with early intervention risk assessment and patient management in burn care settings.It was a cross-sectional and prospective study.This study examines the distribution of blood albumin and C-reactive protein (CRP) levels in 81 burn victims, using gender and age as subgroups.Serum albumin levels showed that 61.7% of patients had hypoalbuminemia (<3.4 g/dL), whereas only 21.0% had normal levels (3.4-5.5 g/dL), and 17.3% had high values (>5.5 g/dL). In terms of gender, hypoalbuminemia was observed in both males (23/36) and females (27/45), suggesting a pervasive imbalance in inflammation and nutrition.(CRP), an acute-phase inflammatory marker, was increased (>5.0 mg/dL) in 21% of patients and normal(0.3–5.0mg/dL) in 79% of patients; significantly more males (10) than females (7) displayed elevated values.In terms of age, hypoalbuminemia was most common in the 1–20 age group (74.5%), followed by the 21–40 and 41–60 age groups (86.7%). Similarly, 26.7% of both older groups and 17.6% of the youngest group had CRP elevation. These findings show a significant prevalence of low albumin levels and systemic inflammation in burn patients, particularly those over the age of 65.The findings emphasize the importance of providing early nutritional assistance and monitoring inflammation in burn care settings in order to improve prognosis and prevent complications.